Law
- Soror Violette Anderson - First black woman to practice law before the U.S. Supreme court
- Soror Bernette J. Johnson —First black female State Supreme Court Justice in Louisiana
- Soror Honorable Andrei Ellen Lee —First black General Session Judge in Nashville , Tennessee
- Soror Honorable Tomie T. Green —First female and first African American female elected Circuit Judge in the 7th Judicial District—State of Mississippi
- Soror Honorable Patricia Wise —First African American Chancery Judge elected Chancery Judge in the 5th Judicial District State of Mississippi. First woman elected president of the African American Magnolia Bar Association State of Mississippi
- Soror Honorable Eleanor Faye Peterson —First black woman elected District Attorney in the State of Mississippi. 1st African American and 1st Female elected District Attorney in the 7th Judicial District—State of Mississippi
Politics
- Soror Curlie E. McGruder —Civil Rights Activist
Entertainment
- Soror Esther Rolle —Actress
- Soror Sheryl Underwood —Comedian
- Soror Dr. Tonea H. Stewart —Actress and first African American to star and later direct at the New Stage Theatre in Jackson , Mississippi.
- Soror Syleena Johnson—Singer
Education
- Soror Dr. Elizabeth D. Koontz —First black president of the National Education Association
- Soror Dr. Joyce Payne —Thurgood Marshall Scholarship Fund founder
